Pathophysiology atresia ani

The occurrence of imperforate anus due to congenital abnormality in which the current process is not complete embryonic development in the process of development of the anus and rectum. In subsequent developments behind the growing tip of the tail of a cloaca which also will develop into genitor urinary and anoretal structure.
Atresia ani is due to incomplete migration and development of the colon between 7-10 weeks during fetal development. The failure occurred because of abnormalities in the uterus and vagina, or also in the process of obstruction. Imperforate anus occurs in the absence of an exit opening of the colon rectum, causing feces can not be excluded.
Clinical manifestations caused by obstuksi and the 'fistula. Obstuksi This resulted in abdominal distension, fluid sequestration, vomiting with all its consequences fistel If the urine flows through to the rectum, the urine will be absorbed resulting in acidosis hiperchloremia, otherwise feces to flow towards the urinary tract causing recurrent infections. In these circumstances will usually be formed fistula between the rectum with the surrounding organs. 90% in women with fistula to the vagina (rektovagina) or perineal (rektovestibuler). The males are usually a high position, generally leading to vesika urinary fistula or to the prostate (rektovesika) at low position fistula leading to the urethra (rektourethralis).